Alheli Delgado Hernandez
Hospital General de Occidente, Mexico
Title: Analysis of the joint and a posteriori probability between primary empty sella, its comorbidities and audiovestibular pathology
Biography
Biography: Alheli Delgado Hernandez
Abstract
Primary empty sella is a herniation of the sellar diaphragm into the pituitary space. It is an incidental finding and patients may manifest neurological, ophthalmological and/or endocrine disorders. Episodes of vertigo, dizziness and hearing loss have been reported.To determine the conditional probability, as well as the statistical dependency, through the Bayesian analysis in patients with primary empty sella and audio vestibular disorders. Individuals who attended the National Rehabilitation Institute from January 2010 to December 2011, diagnosed with primary empty sella and audiovestibular disorders. An analysis was performed on a sample of 18 patients with a diagnosis of primary empty sella confirmed with magnetic resonance studies and who had signs of vertigo, hearing loss and dizziness. Of the 18 patients studied, 3 (16.66%) had primary empty sella as the only clinical evidence. In 9 patients (50%) empty sella was associated with vertigo and 16 patients (88.88%) were diagnosed with hearing loss with sensorineural hearing loss being the most frequent (77.77%). The intersection between the proportions of primary empty sella with the presence and type of hearing loss was calculated. Thus for sensorineural hearing loss, the calculated ratio was P(AB)=0.6912 and for conductive and mixed hearing loss the value of P(AB)=0.0493 in both cases.
Conclusions: Bayesian analysis and conditional probability enables the dependence between two or more variables to be calculated. In this study both mathematical models were used to analyze comorbidities and audiovestibular disorders in patients diagnosed with primary empty sella.