Digital Pathology Applications and Research Case Studies

Prior to slide digitization, skilled pathologists examined clinical trial data to determine evidence of disease and diagnose disease by reviewing glass specimen slides utilizing microscopes. To acquire interpretations, more than a few sets of slides were arranged from each patient’s tissue block, each slide comprising a different level of tissue, and shipped to reviewers. Digital pathology and the implementation of image analysis have grown rapidly in the last few years. This is mostly due to the implementation of whole slide scanning, improvements in software and computer processing capacity and the increasing position of tissue-based research for biomarker discovery and stratified medicine. Digital pathology and image analysis have significant roles across the drug/companion diagnostic improvement pipeline including bio banking, molecular pathology, tissue microarray analysis and these significant developments are reviewed.

  • H&E nuclear quantification
  • IHC Cell membrane quantification
  • Digital imaging practical applications
  • Anatomic pathology digital imaging applications

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