Day 2 :
Keynote Forum
Dongfeng Tan
University of Texas MD Anderson Cancer Center, USA
Keynote: Digital pathology: Update of digital pathology in practice in USA and China
Time : 09:00
Biography:
Dongfeng Tan has received his Medical training from Tongji Medical University (1978-1987) in China and Essen University (1987-1990) in Germany. He did his Postdoctorship at Columbia University Medical Center in New York (1990-1994). After Pathology Residency at Yale University Medical Center (1994 to 1998), he completed an Oncologic Surgical Pathology Fellowship at Memorial Sloan-Kettering Cancer Center in New York. He has joined Roswell Park Cancer Institute as an Assistant Professor of Pathology in 1999 and was promoted to an Associate Professor of Pathology at The University of Texas (UT) Health Science Center at Houston. He has joined the Faculty of The University of Texas MD Anderson Cancer Center in 2006 and he is currently a Professor of Pathology and Laboratory Medicine and Medical Oncology at MD Anderson Cancer Center. He holds joint Professorship in more than 20 universities in the world. He is a Consultant at KingMed Diagnostics.
Abstract:
Digital pathology practices in USA and China will be presented and discussed. It covers three tracks – clinical services and education and research topics. Examples and models of digital pathology practice will be shared, including international digital pathology consultation. Industry standards and their contributions to the advancement in patient care as well as integration of digital pathology into multi-disciplinary are to be discussed.
Keynote Forum
Dominique Bazin
University Pierre and Marie Curie, France
Keynote: Combining field effect scanning electron microscopy, deep UV, fluorescence, Raman, classical and synchrotron radiation Fourier transform infra-red spectroscopy in the study of crystal-containing kidney biopsies
Time : 10:00
Biography:
Dominique Bazin has completed his Masters in Physics at University of Paris 11, Orsay in 1985 and PhD in Solid State Physics, University of Paris 11 in 1992. He was a visitor (14 months) in Physics Department at North Carolina State University in 1997. Since 2013 he works at LCMCP-UPMC University. He has published more than 200 papers in peer reviewed journals including NEJM.
Abstract:
Crystal formation in kidney tissue is increasingly recognized as a major cause of severe or acute renal failure. Kidney biopsies are currently performed and analyzed using different staining procedures. Unfortunately, none of these techniques are able to distinguish the different Ca phosphates (e.g., amorphous or nanostructured Ca phosphate apatite, octacalcium phosphate, brushite) or Ca oxalates (whewellite and weddellite). Moreover, the crystal’s morphology, a structural parameter proven as major information to the clinician regarding kidney stones, is not taken into account. Such major limitations call for a different research approach, based on physicochemical techniques. Here we propose classical observations through field-emission scanning electron microscopy experiments combined with energy dispersive spectroscopy as well as measurements through Raman and µFourier transform Infra-Red Spectroscopy. If necessary, in the case of microcrystals, observations using cutting edge technology such as Synchrotron Radiation (SR)-FTIR or SR-UV visible spectroscopy can be subsequently performed on the same sample. Taken together this set of diagnostic tools will help clinicians gather information regarding the nature and the spatial distribution at the sub-cellular scale of different chemical phases present in kidney biopsies as well as on the crystal morphology and therefore obtain more precise diagnosis.
- Strategy and Technology
Digital Image Analysis
Telepathology
Digital Pathology Applications and Research Case Studies
Anatomic Pathology
Pathology informatics